INTRODUCTION

The potential of stem cell research for tissue engineering-based therapies and regenerative medicine clinical applications has become well established. In 2006, Chung pioneered the first entire organ transplant using adult stem cells and a scaffold for clinical evaluation. With this a new milestone was achieved, with seven patients with myelomeningocele receiving stem cell-derived bladder transplants resulting in substantial improvements in their quality of life. While a bladder is a relatively simple organ, the breakthrough highlights the incredible benefits that can be gained from the cross-disciplinary nature of tissue engineering and regenerative medicine that encompasses stem cell research and stem cell bioprocessing.

DEVELOPMENT OF BIOPROCESS TECHNOLOGIES

The development of bioprocess technologies for the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic as therapeutics necessitates the application of engineering principles and practices to achieve control, reproducibility, automation, validation and safety of the process and the product. This review aims to address the principles required for successful stem cell bioprocessing so that they can be applied deftly to clinical applications. For further explanation regarding particular key point based on stem cell you can submit here or E-mail: biochemical@scholarlypub.com.

ADULT STEM CELL

Adult stem cells, or somatic stem cells, are undifferentiated cells found throughout the adult body. They reside within specific niches in the different organs where they produce cells that regenerate damaged tissue and replace dying cells. Adult stem cells have been used clinically since the 1950s when stem cell transplantation was pioneered using bone marrow-derived stem cells. Since then, other types of adult stem cells have been identified in the body, which have offered alternative tissue repair possibilities and originate from easier to harvest cell sources, such as fat, skin, olfactory cells and peripheral blood, Haemopoietic stem cells can be isolated from several sources besides the adult bone marrow.

The Journal of Biochemical Engineering and Bio-process Technology aims to create advance techniques depending on future 2020 were high quality research papers on all topics related to Biochemical and Bioprocess technology topics. The open access journal is published by OMICS International who hosts more than 350 open access peer-reviewed journals as well as organizes more than 100 International scientific Conferences.