Coronaviruses typically cause common cold symptoms, but two beta coronaviruses — SARS-CoV-1 and Middle East respiratory syndrome coronavirus (MERS-CoV) — can cause severe pneumonia, respiratory failure, and death. In late 2019, infection with a novel beta coronavirus, subsequently named SARS-CoV-2, was reported in people who had been exposed to a seafood market in Wuhan, China, where live animals were sold. Since then, there has been rapid spread of the virus, leading to a global pandemic of Covid-19. Here, we discuss the presentation and management of Covid-19 in patients with mild or moderate illness, as well as prevention and control of the infection. Discussion of Covid-19 that occurs in children and during pregnancy and of severe disease is beyond the scope of this article.`

• Covid-19 (the illness caused by SARS-CoV-2) has a range of clinical manifestations, including cough, fever, malaise, myalgias, gastrointestinal symptoms, and anosmia.
• Diagnosis of Covid-19 is usually based on detection of SARS-CoV-2 by PCR testing of a nasopharyngeal swab or other specimen.
• Evaluation and management of Covid-19 depends on the severity of the disease; patients with mild disease typically recover at home.
• Patients with moderate or severe Covid-19 are usually hospitalized for observation and supportive care.
• There are no proven therapies for Covid-19; thus, referral of patients to clinical trials is critical.
• Infection control and prevention efforts center on personal protective equipment for health care workers, social distancing, and testing.

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