I would like to introduce Journal of Pharmaceutics and Drug delivery Research which is an open access peer-reviewed journal that aims to provide a medium to accelerate and disseminate scientific knowledge on Drug Delivery System, Drug Design & Development, and Drug Metabolism etc.

On the eve of new year we giving discount on membership, you can Take Membership in our Journal and publish 7 to 8 articles in our journal per year.

We publish all sorts of academic papers including Research, Review, Case Report, Short communication, Commentary, Conference proceedings etc.

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.  By definition, when a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered via other routes (such as orally), its bioavailability generally decreases (due to incomplete absorption and first-pass metabolism) or may vary from patient to patient. Bioavailability is one of the essential tools in pharmacokinetics, as bioavailability must be considered when calculating dosages for non-intravenous routes of administration.

For dietary supplements, herbs and other nutrients in which the route of administration is nearly always oral, bioavailability generally designates simply the quantity or fraction of the ingested dose that is absorbed. Bioavailability is defined slightly differently for drugs as opposed to dietary supplements primarily due to the method of administration and Food and Drug Administration regulations.

Bioavailability of a drug is largely determined by the properties of the dosage form, which depend partly on its design and manufacture. Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. Chemical equivalence indicates that drug products contain the same active compound in the same amount and meet current official standards; however, inactive ingredients in drug products may differ. Bioequivalence indicates that the drug products, when given to the same patient in the same dosage regimen, result in equivalent concentrations of drug in plasma and tissues. Therapeutic equivalence indicates that drug products, when given to the same patient in the same dosage regimen, have the same therapeutic and adverse effects.

Age, sex, physical activity, genetic phenotype, stress, disorders (eg, achlorhydria, malabsorption syndromes), or previous GI surgery (eg, bariatric surgery) can also affect drug bioavailability. Chemical reactions that reduce absorption can decrease bioavailability.

Journal of Pharmaceutics and Drug Delivery Research (ISSN: 2325-9604) is now accepting the submissions for upcoming issue and welcomes author submission of original and significant contributions.

Articles can be submitted online or revert back to this mail id: drugres@peerjournal.org

Your acknowledgement and response is highly appreciated. Please contact us for any further query or assistance in this regard.

Thanks & Regards,

Subhana Quadri
Journal Coordinator
Journal of Pharmaceutics and Drug Delivery
drugdelivary@peerreviewedjournal.org
Scitechnol 
Whtasapp No: 44-20-386-84024