The hydrophobic effect is the observed tendency of non-polar substances to accumulate in an aqueous solution and remove water molecules.The term hydrophobic simply means water-fearing, and describes the division of water and non-polar substances, which maximizes the bonding of hydrogen between water molecules and minimizes the area of contact between water and non-polar molecules. The hydrophobic effect in terms of thermodynamics is the free energy change of the water that surrounds a solute. A positive free energy change of the surrounding solvent indicates hydrophobicity, whereas hydrophilicity is implied by a negative free energy change. Comment your views through Email: chemengineerapp@scitecjournals.com We are accepting Submission regarding the chemistry field directly online https://www.scitechnol.com/submission/ For more information check our website https://www.scitechnol.com/ you can also apply for membership or subscription.