The human reproductive system includes the male reproductive system which functions to produce and deposit sperm; and the female reproductive system which functions to produce egg cells, and to protect and nourich the fetus until birth. Humans have a high level of sexual differentiation. In addition to differences in nearly every reproductive organ, there are numerous differences in typical secondary sex characteristics. Human reproduction usually involves internal fertilization by sexual intercourse. In this process, the male inserts his penis into the female's vagina and ejaculates semen, which contains sperm. A small proportion of the sperm pass through the cervix into the uterus, and then into the Fallopian tubes for fertilization of the ovum. Only one sperm is required to fertilize the ovum. Upon successful fertilization, the fertilized ovum, or zygote, travels out of the fallopian tube and into the uterus, where it implants in the uterine wall. This marks the beginning of gestation, better known as pregnancy, which continues for around nine months as the foetus develops. When the foetus has developed to a certain point, pregnancy is concluded with childbirth, involving labor. During labor, the muscles of the uterus contract and the cervix dilates over the course of hours, and the baby passes out of the vagina. Human infants are completely dependent on their caregivers, and require high levels of parental care. Infants rely on their caregivers for comfort, cleanliness, and food. Food may be provided by breastfeeding or formula feeding.

The development of the reproductive system and the development of the urinary system are closely tied in with the development of the human fetus. Despite the differences between the adult female and male are derived from the intermediate mesoderm. The three main fetal precursors of the reproductive organs are the Wolffian duct, the Müllerian ducts, and the gonads. Endocrine hormones are a well-known and critical controlling factor in the normal differentiation of the reproductive system. The Wolffian duct forms the epididymis, vas deferens, ductus deferens, ejaculatory duct, and seminal vesicle in the male reproductive system, but essentially disappears in the female reproductive system. The reverse is true for the Müllerian duct, as it essentially disappears in the male reproductive system and forms the Fallopian tubes, uterus, and vagina in the female system. In both sexes the gonads go on to form the testes and ovaries; because they are derived from the same undeveloped structure, they are considered homologous organs. There are a number of other homologous structures shared between male and female reproductive systems. However, despite the similarity in function of the female Fallopian tubes and the male epididymis and vas deferens, they are not homologous but rather analogous structures as they arise from different fetal structures.

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