The Journal Focuses on inhaled particles, lung regions, deposition mechanisms, targeting, drug delivery. Inhaled particles are carried with the tidal air through the respiratory system. The lungs are enclosed by the pleurae, which are attached to the mediastinum. Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance. Targeted drug delivery is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to others. The treatment of diseases by respiratory drug delivery offers a noninvasive route to deliver either topically active medications or systemic drugs.

In Humans Inhaled particles are carried with the tidal air through the respiratory system. However, because of forces acting upon the particles, their tracks are different from air stream lines. The most important mechanical forces are gravity, inertia, and impulse transfer from collisions with gas molecules.

Particle behavior in the human respiratory tract is well understood and can be used to

(1) Estimate particle deposition in all regions of the respiratory tract for any aerosol respired at any pattern, and

(2) Optimize targeting of all regions of the respiratory tract in respiratory drug delivery.

Extra thoracic and alveolar regions can effectively be targeted with mono-disperse and polydisperse aerosols respired steadily. Effective targeting of the bronchial region can only be achieved with bolus inhalations. When particles are suspended in a gas heavier than air, targeting the alveolar region can be enhanced.

Best Regards,
Editorial Manager
Journal of Pharmaceutical Sciences & Emerging Drugs
Email: editor.jpsed@peerjournal.org