The Journal of Pharmaceutical Sciences & Emerging Drugs  (JPSED) promotes latest research that makes a significant contribution in advancing knowledge of scientific disciplines that are critical to the discovery and development of new drugs and therapies. Journal emphasizes on all aspects of the pharmaceutical sciences which includes a wide range of fields in its discipline like Pharmacology, Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Drug Metabolism, Drug Action, Drug Delivery, Drug Discovery, Drug Targeting and Clinical Sciences.

The Journal focuses on cytochrome P450, drug metabolism and inter-species differences. Cytochromes P450 (CYP) is enzymes known for their role in metabolism of compounds of a rather nonpolar character. Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. For the development of new drugs, evaluation of drug-drug interactions with already known compounds, as well as for better understanding of metabolism pathways of various toxicants and pollutants, we studied the drug metabolism mediated by cytochromes P450. The experimental approach is based on animal drug-metabolizing systems. From the ethical as well as rational reasons, the selection of an appropriate system is crucial. Here, it is necessary to decide on the basis of expected CYP system involved. For CYP1A-mediated pathways, all the commonly used experimental models are appropriate except probably the dog. On the contrary, the dog seems to be suitable for modelling of processes depending on the CYP2D. With CYP2C, which is possibly the most large and complicated subfamily, the systems based on monkey (Maccacus rhesus) may be a good representative. The CYP3A seems to be well modeled by pig or minipig CYP3A29. Detailed studies on activities with individual isolated CYP forms are needed to understand in full all aspects of inter-species differences and variations.

The Journal uses Editorial Manager System for a qualitative and prompt review process. Review processing is performed by the editorial board members of Journal of Pharmaceutical Sciences & Emerging Drugs or relevant experts from other universities or institutes. Minimum two independent reviewer’s approval followed by editor approval is required for the acceptance of any citable manuscript. Authors may submit manuscripts online / through mail id: pharmasci@scitecjournals.com and track their progress through the online tracking system, hopefully to publication.

You can submit your manuscripts as an e-mail attachment to the Editorial Office at editor.jpsed@peerjournal.org
 

Thanks and Best Regards,
Editorial Manager
Journal of Pharmaceutical Sciences & Emerging Drugs
Email: editor.jpsed@peerjournal.org