Angelman syndrome (AS) is a genetic disease that affects the nervous system most of all. Symptoms include a small head with a distinctive facial appearance, serious intellectual disability, cognitive disability, speech difficulties, and difficulties with balance with movement, hallucinations, and issues with sleep. Children tend to have a happy personality and have a special interest in water. The symptoms are usually noticeable within a year. Angelman syndrome is caused by a lack of function of a part of the chromosome 15 inherited from a mother of a person. Most of the time, this is due to the deletion or mutation on that chromosome of the UBE3A Gen. Share your comments on topic Email us: clingenom@peerreviewedjournal.org Submit your submission through direct online link: https://www.scitechnol.com/submission/ For more information visit our website: https://www.scitechnol.com/ We accept more than one paper for one author you can also go for membership.